Why would you limit yourself to five mods? I don't know about such a thing that would make your game crash if you have more. And why would you want to use some WineSkin things? Most of the mods don't use .exe installers except TSLRCM and M4-78EP, which you would install by subscribing to them and mods that use TSLPatcher to patch your game files (you'll only need it when they change something else than textures - .tga, models - .mdl and mdx, always files of both formats, as these are always overrides and scripts - .ncs, as they currently cannot be patched), and these do only content mods that affect existing pieces of the game like most of, but not all quest mods, NPC edits (not necessarily adding NPCs, as that can be handled by scripts) and item changes (again, such edits mostly aren't required for creating new items). Simpler mods do not require you to use the .exe to install them, you just open the .zip (I think that to open compressed folders you don't need an emulator, 7Zip should be available for Mac) and drop the files to a folder you are told to in the ReadMe (usually the Override).