Well, I was actually asking if it's necessary to use the overwrite command on any particular mods since overwrite can cause so many incompatibilities. I'm still a bit new in using the TSLPatcher.
All of my mods generally overwrite, but then again, most don't modify .2da's or dialog.tlk. The ones that do (my dantooine statue, handmaiden4females) do adapt those files, but overwrite other files. Using TSLPatcher to update .dlg's would drive me crazy 0_o